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Disclosure: Financial Investigative Media Limited, which is not owned by Tom Winnifrith but by a trust for his dependants, owns shares in companies mentioned in this article. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from ShareProphets). I have no business relationship with any company whose stock is mentioned in this article.
It sticks in the craw when management award themselves share options at 10p when the share price is 17p. But that is what Premaitha (NIPT) announced yesterday. However
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Comments
C H Ingoldby
This company has been boasting of its ‘game changing’ technology for several years. It is always going to be in the next few months that big things are going to be announced…..
You seem to think that things have totally changed since the days of Vialogy?
Tom Winnifrith
CHI
Old tech was IMHO a joke, the RNS’s were lies. This was a shell. Now you have a new board of winners and a new technology, 100% different. Wait till you see the vid
T
ADVFNPrep
I have been to the Premaitha website, and I find that website little unhelpful. Now, I am sure you have much more information than I have Tom and Steve. But I do wonder, how can you be so sure this is going to have a good shot at success? It is quite easy to impress outsiders with medical tech by cherry picking information.
For example, I have only tracked down 2 papers related to Down screening from the co-inventor and lead scientist Dr. Crea: one of which is a review and both are published in not very impressive journals. These papers also date from 2007 and 2008, not particularly new. I would expect recent publications in high impact journals if this was revolutionary tech. For the 2nd lead scientist, Dr. Shelmerdine, I cannot find any relevant paper.
Personally, I do not know too much about marketing approval processes for screening tests and I am sure that Stephen Little spoke about this. Marketing approval processes can be very time consuming, and are obviously in no way guaranteed.
What about competitors? I actually found this highly cited paper about pretty much the same test: Genet Med 2012:14(3):296–305. The authors are froma company called “Sequenom”. This type of recent highly cited paper is actually what I expected from Premaitha.
I also found the following statement in a recent paper: “Recently, DNA sequencing methods have been introduced on free DNA in maternal plasma, yielding a high screening performance. These methods are expensive and there is a test failure rate. We determined the screening performance of merging the Integrated test with the newer DNA techniques in a protocol that substantially reduces the cost compared with universal DNA testing and still achieves high screening performance with no test failures” Source: PLoS One. 2013;8(3):e58732
Some statements are also misleading. For example: “Compared to traditional methods such as the combined test the IONA® test has both a higher detection rate and a lower false positive rate, leading to improved confidence in the screening result for both pregnant women and their doctors.” What about non-traditional tests? Like Sequenom’s test?